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HEMOSTASIS AND THROMBOSIS UNIT
Director: Giovanni Davì
Phone: +39 0871 541 312
E-Mail gdavi@unich.it
Available Services
• Haemophilia and congenital or acquired haemorrhagic disorders
• Screening of congenital and acquired thrombophilic pattern
• In vivo indices of platelet, endothelial and coagulative activation
• Indices of lipid peroxidation in cardiovascular and inflammatory diseases
• Determinants of F2-isoprostane biosynthesis and inhibition in man
• Functional read-outs of low-grade inflammatory state in cardiovascular disease
On-going studies:
• Double-blind, randomized, placebo controlled study to evaluate the effects of angiotensin II receptor antagonist Irbesartan on in vivo indices of lipid peroxidation and platelet activation in heart failure
• Interaction between inflammation, oxidative stress and platelet activation in rheumatoid arthritis
Completed studies:
• Double-blind, randomized, placebo controlled study to evaluate the effects of acarbose on inflammation, endothelial dysfunction, oxidative stress and platelet activation in patients with early type II diabetes
• Double-blind, randomized, placebo controlled study to evaluate the effects of rosiglitazone on biochemical indexes of inflammation, endothelial dysfunction, oxidative stress and platelet activation in patients carrying type II diabetes treated with metformin
• Role of COX-2 on in vivo platelet activation in essential thrombocytemia
• Time-dependent effect of antiplatelet treatment with aspirin in healthy volunteers
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